"ComicBook.com can exclusively report that the upcoming Dungeons & Dragons movie currently in development by Paramount will focus on a group of adventurers looking for the Eye of Vecna, a powerful artifact that dates back to the earliest days of the game. Vecna is a powerful lich turned god whose hand and eye (remnants from when Vecna was a mortal) grant unspeakable power. Both the Hand and Eye of Vecna come with a terrible cost - in order to use either artifact, the user must remove their existing eye or hand and then replace it with the artifact.
Vecna was a major entity in the Greyhawk campaign setting [...]"
The Hand and Eye of Vecna were among the artifacts that most excited (and corrupted?) my young imagination decades ago!
(Thanks to C. Robichaud for the link to the ComicBook-dot-com article.)